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Updated: Aug 31, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Bullous autoimmune dermatoses of the mucous membranes]
Dario Didona1, Julia Hinterseher2, Rüdiger Eming2,3
1Klinik für Dermatologie und Allergologie, Philipps-Universität Marburg, Marburg, Deutschland. didona@med.uni-marburg.de.
Abstract:
Autoimmune bullous diseases (AIBD) comprise a group of organ-specific autoimmune diseases which are characterised by the production of autoantibodies against adhesion molecules and structural proteins of skin and mucosae. Depending on the target protein, AIBD are classified into intraepidermal (pemphigus group) and subepidermal (pemphigoid group, epidermolysis bullosa acquisita, dermatitis herpetiformis) blistering disorders. Depending on the clinical entity, patients can develop blisters, pustules, erosions, and erythema on the skin and mucosae.
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