Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

2.0K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of Primary Rhegmatogenous Retinal Detachment Repair With Adjunctive Mitomycin C.

Journal of vitreoretinal diseases·2026
Same author

Visual outcomes after one-stage versus two-stage surgery for intraocular foreign body removal and open globe repair.

Scientific reports·2026
Same author

Incremental Predictive Value of Preoperative Macular Optical Coherence Tomography for Postoperative Visual Acuity After Phacoemulsification Cataract Surgery: A Retrospective Cohort Study.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Validation of the "FIRST-ROP" Algorithm at a Neonatal Intensive Care Unit Tertiary Center over Three Decades.

American journal of ophthalmology·2026
Same author

Pediatric Macular Hole Outcomes with Surgical and Nonsurgical Management: An IRIS® Registry Study.

Ophthalmology. Retina·2026
Same author

Endophthalmitis associated with intravitreal injection: rates, culture results, and visual acuity outcomes.

Retina (Philadelphia, Pa.)·2026

Related Experiment Video

Updated: Aug 31, 2025

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies
12:28

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

Published on: March 12, 2022

3.7K

RETINAL VASCULAR DISEASE IN LIMB-GIRDLE MUSCULAR DYSTROPHY.

Abdulla R Shaheen1, Nicolas A Yannuzzi1, Thomas Kennedy2

  • 1Bascom Palmer Eye Institute, Miami, FL.

Retinal Cases & Brief Reports
|August 25, 2022
PubMed
Summary

Limb-girdle muscular dystrophy (LGMD) can cause bilateral retinal vascular occlusive disease. This case highlights potential vascular smooth muscle dysfunction in LGMD patients.

More Related Videos

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.5K
Measuring Retinal Vessel Diameter from Mouse Fluorescent Angiography Images
04:04

Measuring Retinal Vessel Diameter from Mouse Fluorescent Angiography Images

Published on: May 19, 2023

776

Related Experiment Videos

Last Updated: Aug 31, 2025

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies
12:28

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

Published on: March 12, 2022

3.7K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.5K
Measuring Retinal Vessel Diameter from Mouse Fluorescent Angiography Images
04:04

Measuring Retinal Vessel Diameter from Mouse Fluorescent Angiography Images

Published on: May 19, 2023

776

Area of Science:

  • Ophthalmology
  • Genetics
  • Neurology

Background:

  • Limb-girdle muscular dystrophy (LGMD) is a group of inherited muscle-weakening diseases.
  • LGMD results from genetic defects in sarcolemma proteins, crucial for muscle fiber structure.
  • Retinal vascular abnormalities have been observed in other muscular dystrophies.

Observation:

  • A 34-year-old woman with central retinal vein occlusion was diagnosed with LGMD.
  • Ultra-wide-field fluorescein angiography revealed peripheral retinal vein occlusion and venular segmental staining.
  • The findings were asymmetric between the eyes.

Findings:

  • This case reports bilateral retinal vascular occlusive disease in a patient with LGMD.
  • Evidence suggests retinal vascular smooth muscle dysfunction in LGMD.
  • The observed vascular issues are analogous to those seen in other muscular dystrophies.

Implications:

  • LGMD may be associated with significant retinal vascular complications.
  • Ophthalmologists should consider LGMD in patients presenting with unexplained retinal vascular occlusive disease.
  • Further research is warranted to understand the link between LGMD and retinal vascular health.