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Related Experiment Video

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Blood Flow Imaging with Ultrafast Doppler
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Flow imaging using differential Golay encoded ultrasound.

A Nowicki1, J Tasinkiewicz1, I Trots1

  • 1Ultrasound Department, Institute of Fundamental Technological Researches of the Polish Academy of Sciences, Warsaw, Poland.

Ultrasonics
|August 25, 2022
PubMed
Summary

We developed differential compression of Golay encoded ultrasound (DCGEU) to visualize slow blood flow in small vessels. This new method improves sensitivity and suppresses static echoes for clearer imaging.

Keywords:
Classical beamformingCoded excitationFlow imagingUltrasound imaging

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Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Biomedical Engineering

Background:

  • Visualizing slow blood flow in small vessels is challenging with conventional ultrasound.
  • Existing methods struggle to differentiate moving blood from static tissue echoes.

Purpose of the Study:

  • To introduce and validate a novel differential compression of Golay encoded ultrasound (DCGEU) method.
  • To enhance visualization of slow (<1cm/s) blood-mimicking fluid flow in small diameter tubes.

Main Methods:

  • DCGEU synthesizes B-mode frames, then visualizes differential beamformed radio frequency (RF) echoes.
  • Utilized complementary Golay coded sequences (CGCS) for improved sensitivity to small backscattered echoes.
  • Validated using numerical simulations and experimental data in flow phantoms with small tubes (1-4.5mm diameter).

Main Results:

  • DCGEU successfully visualized slow flow in small tubes (1-4.5mm diameter).
  • The method suppressed static echoes, highlighting moving scatterers within the vessel.
  • Achieved virtually angle-independent detection compared to conventional short pulse methods.

Conclusions:

  • DCGEU offers a promising approach for sensitive visualization of slow blood flow in microvasculature.
  • The method enhances image quality by reducing static clutter.
  • DCGEU demonstrates superior performance over conventional techniques for specific flow imaging applications.