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In-hospital and Readmission Outcomes With Percutaneous Balloon Mitral Valvuloplasty

Ahmed Elkaryoni1, Fizza Hussain1, Nicole Chahine1

  • 1Division of Cardiovascular Disease, Loyola University Medical Center, Loyola Stritch School of Medicine, Maywood, IL.

Current Problems in Cardiology
|August 25, 2022
PubMed

Insights

Percutaneous balloon mitral valvuloplasty (PBMV) outcomes for rheumatic and non-rheumatic mitral stenosis (MS) showed no significant changes in mortality or readmission over time. However, non-rheumatic MS patients experienced a trend toward increased hospitalizations post-PBMV.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Public Health

Background:

  • Rheumatic mitral stenosis (MS) is the primary indication for percutaneous balloon mitral valvuloplasty (PBMV).
  • Limited data exist on PBMV efficacy in non-rheumatic MS, particularly in regions with low rheumatic fever incidence.
  • Understanding PBMV outcomes in diverse MS etiologies is crucial for global cardiovascular care.

Purpose of the Study:

  • To analyze trends in in-hospital mortality and 30-day readmission following PBMV for rheumatic versus non-rheumatic MS.
  • To evaluate changes in the 90-day hospitalization rate before and after PBMV in both patient groups.
  • To assess the impact of PBMV on outcomes in a contemporary US cohort.

Main Methods:

  • Retrospective analysis of the Nationwide Readmission Database (2016-2019).
  • Inclusion of adult patients undergoing PBMV for either rheumatic or non-rheumatic MS.
  • Comparison of in-hospital mortality, 30-day readmission, and 90-day hospitalization rates between etiologies and over time.

Main Results:

  • A total of 1109 PBMV hospitalizations were analyzed (86.1% rheumatic MS, 13.9% non-rheumatic MS).
  • No statistically significant changes in in-hospital mortality or 30-day readmission were observed over time for either group.
  • While overall trends were stable, non-rheumatic MS patients showed a signal of increased in-hospital mortality and a 29% relative increase in 90-day hospitalizations post-PBMV.

Conclusions:

  • PBMV demonstrated stable outcomes regarding mortality and readmission for both rheumatic and non-rheumatic MS between 2016-2019.
  • A concerning trend of increased hospitalizations was observed in non-rheumatic MS patients after PBMV.
  • Further research is warranted to clarify the role and optimize PBMV for non-rheumatic MS etiologies.

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