[Visual evoked potentials and their relation to fundus oculi changes in patients with subacute sclerosing...

The results of 634 determinations of visual evoked potentials in 110 cases of SSPE are presented. The determinations were repeated many times in successive stages of the disease and were compared with findings obtained during eye fundus examinations. A statistically significant correlation was found between these potentials and changes in the fundus involving the optic disc and macula, and increasing abnormalities of the potentials in successive stages of the disease with their complete disappearance in the last stages. Visual evoked potential determination is regarded by the authors as a valuable diagnostic factor in early stages of the disease and as an additional source providing information about the degree of visual system damage with progression of the pathological process.