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Management of Pediatric Urinary Tract Infections: A Delphi Study
Giovanni Autore1, Luca Bernardi1, Claudio La Scola2
1Pediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Insights
This study addresses pediatric urinary tract infections (UTIs), aiming to standardize management and combat antimicrobial resistance. It provides updated guidelines for healthcare professionals to improve treatment outcomes and judicious antibiotic use in children.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Management of Urinary Tract Infections
- Antimicrobial Resistance
Background:
- Urinary tract infections (UTIs) are highly prevalent in children, contributing significantly to antibiotic use and hospitalizations.
- Current pediatric UTI management faces challenges due to evolving antimicrobial resistance patterns and clinical practice variations.
Purpose of the Study:
- To evaluate consensus on pediatric UTI management within the Emilia-Romagna Region, Italy.
- To assess the need for updating current clinical recommendations for pediatricians and pediatric surgeons based on recent literature.
- To provide standardized, evidence-based guidelines for managing pediatric UTIs and optimizing antibiotic stewardship.
Main Methods:
- Literature review of recent studies on pediatric UTI management.
- Consensus-building among primary care pediatricians, hospital pediatricians, and pediatric surgeons.
- Development of updated clinical recommendations and statements.
Main Results:
- The study generated a comprehensive and up-to-date collection of statements on pediatric UTI management procedures.
- The consensus aims to guide physicians, standardize clinical approaches, and prevent antibiotic overuse and misuse.
Conclusions:
- Updated guidelines are proposed to standardize pediatric UTI management and address antimicrobial resistance.
- Further randomized controlled trials are necessary to refine therapeutic strategies, particularly concerning antimicrobial resistance and long-term antibiotic prophylaxis efficacy in children.
Abstract:
Urinary tract infection (UTI) is one of the most common infectious diseases in the pediatric population and represents a major cause of antibiotic consumption and hospitalization in children. Considering the ongoing controversies on the management of pediatric UTI and the challenges due to increasing antimicrobial resistance, the aim of the present study was to evaluate the level of agreement on UTI management in pediatric age in Emilia-Romagna Region, Italy, and to assess on the basis of recent studies whether there is the need to change current recommendations used by primary care pediatricians, hospital pediatricians, and pediatric surgeons in everyday clinical practice to possibly improve outcomes. This consensus provides clear and shared indications on UTI management in pediatric age, based on the most updated literature. This work represents, in our opinion, the most complete and up-to-date collection of statements on procedures to follow for pediatric UTI, in order to guide physicians in the management of the patient, standardize approaches, and avoid abuse and misuse of antibiotics. Undoubtedly, more randomized and controlled trials are needed in the pediatric population to better define the best therapeutic management in cases with antimicrobial resistance and real usefulness of long-term antibiotic prophylaxis.
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