Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

227
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
227
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

190
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
190
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

303
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
303
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

315
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
315
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

414
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
414
Pneumonia IV: Management01:28

Pneumonia IV: Management

433
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
433

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of artificial intelligence and digital technology-based diagnostic tools for communicable and non-communicable diseases in Africa.

African journal of laboratory medicine·2025
Same author

Geriatric drug delivery - barriers, current technologies and the road ahead.

Journal of drug targeting·2024
Same author

Characterization of Prototype Gummy Formulations Provides Insight into Setting Quality Standards.

AAPS PharmSciTech·2024
Same author

Leading Paediatric Infectious Diseases-Current Trends, Gaps, and Future Prospects in Oral Pharmacotherapeutic Interventions.

Pharmaceutics·2024
Same author

State of the art in pediatric nanomedicines.

Drug delivery and translational research·2024
Same author

A child-friendly anti-infective gummy formulation: Design, physicochemical, micromechanical, and taste sensory evaluation.

Drug delivery and translational research·2023

Related Experiment Video

Updated: Aug 31, 2025

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

18.9K

Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?

Lehlogonolo N F Maphalle1, Bozena B Michniak-Kohn2,3, Modupe O Ogunrombi4

  • 1Division of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0208, South Africa.

Children (Basel, Switzerland)
|August 26, 2022
PubMed
Summary

Pediatric tuberculosis (TB) is a critical global health issue affecting children and adolescents. More research is urgently needed to improve the management and outcomes for pediatric TB cases.

Keywords:
COVID-19coronavirus pandemicdiagnosisextrapulmonary tuberculosispediatricspreventionpulmonary tuberculosistreatment

More Related Videos

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

1.9K
A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
10:29

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis

Published on: March 24, 2017

7.9K

Related Experiment Videos

Last Updated: Aug 31, 2025

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

18.9K
An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

1.9K
A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
10:29

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis

Published on: March 24, 2017

7.9K

Area of Science:

  • Public Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Tuberculosis (TB) remains a leading cause of mortality and morbidity in children and adolescents worldwide.
  • Children and adolescents are highly vulnerable to severe TB, with potential for fatal outcomes and disease transmission.
  • Pediatric TB is under-prioritized in research and health programs, with a focus on adult management strategies.

Purpose of the Study:

  • To highlight the urgent need for novel research and improved strategies specifically for managing pediatric tuberculosis.
  • To address the neglect of infection and disease control in minors susceptible to TB.
  • To counteract the negative impact of the COVID-19 pandemic on global TB eradication efforts.

Main Methods:

  • This study is a review and synthesis of current knowledge on pediatric tuberculosis management.
  • It analyzes the existing gaps in research and clinical practice for this vulnerable population.
  • It emphasizes the need for dedicated research initiatives and improved public health interventions.

Main Results:

  • Pediatric TB management is significantly under-resourced and under-researched compared to adult TB.
  • The COVID-19 pandemic has exacerbated challenges in TB diagnosis, treatment, and prevention globally.
  • There is a critical lack of tailored interventions and research for children and adolescents with TB.

Conclusions:

  • Novel research and dedicated strategies are essential to improve the health and longevity of children and adolescents affected by TB.
  • Increased focus on pediatric TB is crucial for achieving global TB eradication goals.
  • Addressing the specific needs of minors in TB control programs is a public health imperative.