Computer-Based Cognitive Training in Children with Primary Brain Tumours: A Systematic Review

Area of Science:

• Neuroscience
• Rehabilitation Medicine
• Pediatric Oncology

Background:

• Late neurocognitive sequelae significantly impact the quality of life for brain tumor survivors.
• Digital interventions, including apps and software, are emerging as innovative tools for cognitive rehabilitation.

Purpose of the Study:

• To systematically review current evidence on digital interventions for cognitive rehabilitation in pediatric brain tumor survivors.
• To identify trends and evaluate the effectiveness of these innovative approaches.

Main Methods:

• A systematic literature review was conducted.
• Included studies focused on patients diagnosed with brain tumors before age 21 and assessed digital interventions' impact on cognitive outcomes.
• Excluded were case reports, reviews, and other non-original research formats.

Main Results:

• Nine studies involving 152 pediatric brain tumor patients were analyzed.
• Interventions included software like Cogmed, Captain's Log, Fast ForWord, and Nintendo Wii.
• Improvements were noted in working memory, attention, and daily living activities.

Conclusions:

• Digital cognitive interventions appear to enhance cognitive functions such as working memory, attention, and processing speed.
• Some studies indicated transient effects and significant dropout rates, highlighting the need for better patient engagement.
• Larger trials are recommended to confirm efficacy and explore strategies to improve adherence and long-term outcomes.