Normal and abnormal morphology of the corpus callosum

We studied the normal and abnormal morphology of the corpus callosum in 450 midline sagittal magnetic resonance scans. Clinical information was required to differentiate acquired and congenital defects. Four forms of congenital anomalies were observed: focal attenuations, cysts, partial agenesis, and complete agenesis. Acquired changes resulted from hydrocephalus, white matter diseases, vascular accidents, tumor, and trauma.