Evidence for the prostatic origin of gamma-glutamyltranspeptidase activity in human semen

Gamma-glutamyltranspeptidase activity and fructose concentration have been measured in 100 semen samples, in 7 split ejaculates and in the seminal fluid of a patient with congenital absence of ductus deferens and seminal vesicles. Evidence is presented that the prostate is the major source of gamma-glutamyltranspeptidase in human semen.