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Updated: Aug 30, 2025

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling
Published on: February 5, 2019
Osteopathic Treatment for Gastrointestinal Disorders in Term and Preterm Infants: A Systematic Review and
Francesca Buffone1,2,3, Domenico Monacis2,4, Andrea Gianmaria Tarantino1,2
1Division of Paediatric, Manima Non-Profit Organization Social Assistance and Healthcare, 20125 Milan, Italy.
Insights
Osteopathic manipulative treatment (OMT) shows potential benefits for infant gastrointestinal disorders, particularly reducing crying time in colic. However, more high-quality research is needed to confirm effectiveness and allow for broader application.
Area of Science:
- Pediatrics
- Gastroenterology
- Osteopathic Medicine
Background:
- Gastrointestinal (GI) disorders are common in infants.
- Osteopathic manipulative treatment (OMT) is a non-pharmacological approach.
- Evidence on OMT for infant GI issues requires synthesis.
Purpose of the Study:
- To systematically review and meta-analyze the effectiveness of OMT for GI disorders in term and preterm infants.
- To assess OMT's impact on outcomes like crying, feeding, and weight gain.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials and retrospective studies.
- Searched major databases: PubMed, Scopus, Embase, Cochrane, Cinahl, PEDro.
- Included studies comparing OMT to control groups in infants with GI disorders.
Main Results:
- Nine articles met eligibility criteria; five had low risk of bias.
- Meta-analysis of two studies showed significant reduction in crying hours for infantile colic (ES = −2.46).
- Other outcomes (feeding, weight gain) were qualitatively synthesized; OMT was generally safe.
Conclusions:
- OMT demonstrates potential efficacy for some infant GI issues, notably colic.
- Moderate quality evidence exists, but conflicting results and lack of replication studies limit generalization.
- High-quality randomized controlled trials are recommended for robust evidence.
Abstract:
The aim of this systematic review and meta-analysis is to evaluate the effectiveness of osteopathic manipulative treatment (OMT) for gastrointestinal disorders in term and preterm infants. Eligible studies were searched on PubMed, Scopus, Embase, Cochrane, Cinahl, and PEDro. Two reviewers independently assessed if the studies were randomized controlled trials (RCTs) and retrospective studies with OMT compared with any kind of control in term or preterm infants to improve gastrointestinal disorders. Nine articles met the eligibility criteria, investigating OMT compared with no intervention, five involving term infants, and the remaining treating preterm infants. Five studies showed low risk of bias. In the meta-analysis, two studies were included to analyze the hours of crying due to infantile colic, showing statistically significant results (ES = −2.46 [−3.05, −1.87]; p < 0.00001). The quality of evidence was “moderate”. The other outcomes, such as time to oral feeding, meconium excretion, weight gain, and sucking, were presented in a qualitative synthesis. OMT was substantially safe, and showed efficacy in some cases, but the conflicting evidence and lack of high-quality replication studies prevent generalization. High-quality RCTs are recommended to produce better-quality evidence.
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