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COVID-19 Mortality and Related Comorbidities in Hospitalized Patients in Bulgaria
Rositsa Dimova1, Rumyana Stoyanova1, Vesela Blagoeva2
1Department of Health Management and Health Economics, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Insights
COVID-19 mortality is higher in elderly men and those with comorbidities like cardiovascular, metabolic, and respiratory disorders. Factors influencing COVID-19 fatality include hospital admission timing and length of stay.
Area of Science:
- Infectious Diseases
- Epidemiology
- Public Health
Background:
- The COVID-19 pandemic has caused millions of deaths globally.
- Bulgaria faces a high COVID-19 mortality rate, necessitating local research.
- Understanding risk factors for COVID-19 mortality is crucial for public health interventions.
Purpose of the Study:
- To analyze COVID-19 mortality rates in hospitalized patients in Bulgaria.
- To identify common underlying medical conditions associated with COVID-19 deaths.
- To determine factors impacting COVID-19 mortality risk.
Main Methods:
- Retrospective analysis of a descriptive cross-sectional study.
- Data collected from 128,269 hospitalized patients (April 2020 - November 2021).
- Analysis included patient demographics, comorbidities, admission details, and outcomes.
Main Results:
- 5200 COVID-19 hospital admissions; 1470 (33.3%) had a lethal outcome.
- Higher COVID-19 case fatality rate (CFR) observed in the elderly, males, and patients with multiple comorbidities.
- Chronic cardiovascular, metabolic, and respiratory disorders were significant risk factors.
- Shorter hospital stays and rapid admission post-emergency visit correlated with higher mortality.
Conclusions:
- Elderly men with comorbidities face increased COVID-19 mortality risk.
- Prompt medical attention and management of chronic conditions are vital.
- Study highlights specific demographic and clinical factors influencing COVID-19 outcomes in Bulgaria.
Abstract:
Until now, the COVID-19 pandemic has resulted in at least 27 million cases and over 900,000 deaths worldwide. Bulgaria is one of the countries that is the most severely affected by the COVID-19 pandemic, and the mortality rate is among the highest registered in the world. The aim of this study is to investigate and analyze mortality rates due to the fact of COVID-19 in addition to the most common related underlying medical conditions in those hospitalized to outline the factors that have an impact on the mortality rate due to the fact of COVID-19. A descriptive cross-sectional research design with a retrospective analysis was used to collect data from a total of 128,269 hospitalized patients during the period from April 2020 to November 2021. During the study period, the number of hospital admissions due to the fact of COVID-19 was 5200. The patients' mean age was 67.34 (SD ± 19.65), and 51.7% (2689) of the patients were men. Only 10% of out of a total of 5200 patients did not test positive for COVID-19 upon admission based on the antigen or PCR test. Out of all patients, 41.5% had no underlying medical conditions upon presentation, and the remaining 58.5% had diagnosed comorbidities, varying from one to five. One-third (1470) had a lethal outcome, and the remaining 71.7% recovered from the infection and were discharged from the hospital. Based on the analysis of our results, there is definite evidence that the CFR and susceptibility to symptomatic COVID-19 were higher in the elderly, men, and patients with more comorbidities, especially chronic cardiovascular, metabolic, and respiratory disorders, as well as in those admitted to hospital within 6 h after an emergency ward visit and who had a shorter mean hospital stay.
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