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Prevalence, Causes, and Adverse Clinical Impact of Delayed Presentation of Non-COVID-19-Related Emergencies during
Mohammed S Alshahrani1,2, Dunya Alfaraj3, Jehan AlHumaid4
1Emergency Medicine and Intensive Care Departments, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Insights
During the COVID-19 pandemic, over half of emergency patients with non-COVID-19 conditions experienced delayed hospital visits. This delay, often due to fear of infection or restrictions, significantly increased mortality rates.
Area of Science:
- Emergency Medicine
- Public Health
- Infectious Diseases
Background:
- The COVID-19 pandemic significantly disrupted global healthcare, leading to reduced emergency department visits for non-COVID-19 conditions.
- Delayed hospital presentations can negatively impact patient outcomes in acute medical and surgical emergencies.
Purpose of the Study:
- To evaluate the impact of the COVID-19 pandemic on the presentation and outcomes of patients with non-COVID-19-related acute emergencies.
- To identify the prevalence, causes, and clinical outcomes associated with delayed emergency department presentation during the pandemic.
Main Methods:
- A comparative study involving non-COVID-19 patients hospitalized through emergency departments in Saudi Arabia and Bahrain during June-July 2020.
- Patients were categorized into delayed (≥24 hours symptom onset) and non-delayed (<24 hours) groups.
- Outcomes included prevalence of delay, reasons for delay, and 28-day clinical outcomes (mortality, ICU admission, ventilation, surgery).
Main Results:
- A total of 256 non-COVID-19 patients were analyzed; 52% presented with delayed symptoms.
- Fear of COVID-19 (34%) and curfew restrictions (19%) were primary reasons for delay.
- Delayed presentation was associated with significantly higher 28-day mortality (10.4% vs. 2.5%, OR 4.628, p=0.038).
Conclusions:
- Over half of hospitalized patients with non-COVID-19 emergencies experienced delayed presentation during the pandemic.
- Delayed presentation significantly increased the risk of mortality.
- Fear of contracting COVID-19 and pandemic-related restrictions were major contributors to delayed healthcare seeking.
Abstract:
Objective: The coronavirus disease (COVID-19) pandemic has disrupted healthcare systems worldwide, resulting in decreased and delayed hospital visits of patients with non-COVID-19-related acute emergencies. We evaluated the impact of the COVID-19 pandemic on the presentation and outcomes of patients with non-COVID-19-related medical and surgical emergencies. Method: All non-COVID-19-related patients hospitalized through emergency departments in three tertiary care hospitals in Saudi Arabia and Bahrain in June and July 2020 were enrolled and categorized into delayed and non-delayed groups (presentation ≥/=24 or <24 h after onset of symptom). Primary outcome was the prevalence and cause of delayed presentation; secondary outcomes included comparative 28-day clinical outcomes (i.e., 28-day mortality, intensive care unit (ICU) admission, invasive mechanical ventilation, and acute surgical interventions). Mean, median, and IQR were used to calculate the primary outcomes and inferential statistics including chi-square/Fisher exact test, t-test where appropriate were used for comparisons. Stepwise multivariate regression analysis was performed to identify the factors associated with delay in seeking medical attention. Results: In total, 24,129 patients visited emergency departments during the study period, compared to 48,734 patients in the year 2019. Of the 256 hospitalized patients with non-COVID-19-related diagnoses, 134 (52%) had delayed presentation. Fear of COVID-19 and curfew-related restrictions represented 46 (34%) and 25 (19%) of the reasons for delay. The 28-day mortality rates were significantly higher among delayed patients vs. non-delayed patients (n = 14, 10.4% vs. n = 3, 2.5%, OR: 4.628 (CI: 1.296−16.520), p = 0.038). Conclusion: More than half of hospitalized patients with non-COVID-19-related diagnoses had delayed presentation to the ED where mortality was found to be significantly higher in this group. Fear of COVID-19 and curfew restrictions were the main reasons for delaying hospital visit.
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