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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Related Experiment Video

Updated: Aug 30, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Atopic Dermatitis: Background, Objectives and Future Perspectives (Superresponders).

Ricardo Ruiz-Villaverde1, Javier Domínguez-Cruz2, Francisco J Navarro-Triviño1

  • 1Dermatology Department, Hospital Universitario San Cecilio, H.U. San Cecilio, Avda. Conocimiento 33, 18016 Granada, Spain.

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Summary

This special issue explores new insights into atopic dermatitis, focusing on its underlying causes and innovative treatments. Discover the latest research on managing this common skin condition effectively.

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Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Atopic dermatitis (AD) is a complex inflammatory skin disease with increasing prevalence worldwide.
  • Understanding the intricate pathophysiological mechanisms of AD is crucial for developing effective therapies.

Discussion:

  • This special issue highlights recent advancements in understanding AD pathogenesis, including immune dysregulation and genetic factors.
  • Novel therapeutic strategies targeting specific pathways are being explored to improve patient outcomes.

Key Insights:

  • The collection emphasizes the integration of pathophysiological knowledge with emerging treatment options for atopic dermatitis.
  • Research presented offers new perspectives on personalized medicine approaches for AD management.

Outlook:

  • Future research directions include further elucidation of AD biomarkers and the development of long-term, safe, and effective treatments.
  • The ongoing exploration of novel therapeutic targets promises to revolutionize atopic dermatitis care.