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Electrocardiographic Changes Associated with Early Repolarization Pattern in Healthy Young Males
Attila Frigy1,2, Hunor Gábor-Kelemen1, Szabolcs Attila László3
1Department of Cardiology, Clinical County Hospital Mures, 540103 Targu Mures, Romania.
Medicina (Kaunas, Lithuania)
|August 26, 2022
Summary
Early repolarization pattern (ERP) is linked to arrhythmias. Specific ECG changes, like P wave duration and fragmented QRS, may indicate arrhythmogenesis risk in healthy young males with ERP.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Diagnostics
Background:
- Early repolarization pattern (ERP) is increasingly associated with ventricular arrhythmia risk.
- Understanding ERP-related electrocardiogram (ECG) changes is crucial for risk stratification.
Purpose of the Study:
- To investigate specific ECG characteristics associated with ERP in young, healthy males.
- To identify potential markers for atrial and ventricular arrhythmogenesis in individuals with ERP.
Main Methods:
- 12-lead ECG recordings were analyzed in 220 healthy young males.
- Subjects were divided into groups with (n=38) and without ERP.
- 90 ECG characteristics were compared between the groups.
Main Results:
- 22 ECG parameters showed significant differences between subjects with and without ERP (p < 0.05).
- P wave duration and fragmented QRS complexes were more prevalent in the ERP group, suggesting arrhythmogenesis potential.
- Accelerated repolarization was indicated by shorter time-domain repolarization parameters (e.g., Tpeak-Tend interval).
Conclusions:
- Specific ECG features are associated with the early repolarization pattern in young males.
- Further prospective studies are needed to determine the clinical significance of these ECG findings at an individual level.
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