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Hypericum Essential Oils-Composition and Bioactivities: An Update (2012-2022)
Maria-Eleni Grafakou1,2, Christina Barda1, George Albert Karikas3
1Department of Pharmacognosy & Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, 15771 Athens, Greece.
Molecules (Basel, Switzerland)
|August 26, 2022
Summary
This review summarizes recent research on Hypericum essential oils, detailing their chemical makeup and pharmacological effects. Findings explore the link between traditional uses and the bioactivity of these widely distributed plant oils.
Area of Science:
- Phytochemistry
- Pharmacology
- Ethnobotany
Background:
- The Hypericum genus, with over 500 widely distributed species, has a long history of human use.
- Essential oils from Hypericum plants are recognized for their diverse chemical constituents and biological activities.
- Recent scientific interest focuses on understanding the therapeutic potential of these essential oils.
Purpose of the Study:
- To review and synthesize recent literature (2012-2022) on essential oils from the Hypericum genus.
- To present findings on the chemical composition and pharmacological activities (in vitro and in vivo) of Hypericum essential oils.
- To explore the connection between traditional applications and the scientifically validated bioactivity of these oils.
Main Methods:
- Systematic literature search across major scientific databases including PubMed, ScienceDirect, Reaxys, and Google Scholar.
- Compilation and analysis of research articles published between 2012 and 2022.
- Synthesis of data on chemical profiles and documented pharmacological effects.
Main Results:
- Detailed overview of the chemical constituents found in various Hypericum essential oils.
- Summary of in vitro and in vivo studies demonstrating diverse pharmacological activities.
- Exploration of correlations between ethnobotanical uses and observed bioactivities.
Conclusions:
- Hypericum essential oils possess a rich chemical diversity with significant pharmacological potential.
- Recent research supports and expands upon the traditional uses of Hypericum species.
- Further investigation into the bioactivity of Hypericum essential oils is warranted for therapeutic development.
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