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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Related Experiment Video

Updated: Aug 30, 2025

Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery
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Functional Nanoparticles for Enhanced Cancer Therapy.

Chenchen Li1, Yuqing Li1, Guangzhi Li1

  • 1Institute of Urology, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen 518000, China.

Pharmaceutics
|August 26, 2022
PubMed
Summary
This summary is machine-generated.

Functional nanoparticles offer advanced cancer therapy, improving diagnosis and targeted drug delivery beyond traditional chemotherapy. This review explores their progress, challenges, and future clinical applications in oncology.

Keywords:
cancer therapyfunctional nanoparticlesnanotechnology

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Oncology

Background:

  • Cancer remains a leading global cause of death, with conventional chemotherapy presenting significant side effects.
  • Nanoparticle-based drug delivery systems offer a promising alternative to traditional cancer treatments.
  • The integration of nanotechnology into biomedicine has spurred advancements in cancer diagnosis and therapy.

Purpose of the Study:

  • To analyze the progress of functional nanoparticles in cancer therapy.
  • To discuss research gaps and future strategies for the clinical application of these nanomedicines.

Main Methods:

  • Review of current literature on functional nanoparticles in cancer treatment.
  • Analysis of various nano-drug strategies, including stimuli-responsive systems, surface conjugation, and encapsulation.
  • Discussion of challenges and limitations in clinical translation.

Main Results:

  • Functional nanoparticles have demonstrated significant progress in cancer diagnosis, targeted therapy, and personalized treatment.
  • Various nano-drug strategies have shown success in preventing tumor progression.
  • The field is rapidly evolving with promising future potential.

Conclusions:

  • Functional nanoparticles represent a significant advancement in cancer therapy, offering improved efficacy and reduced side effects.
  • Addressing current challenges is crucial for the successful clinical application of nanotechnology in oncology.
  • Continued research and development are essential to fully realize the potential of nanomedicines in fighting cancer.