In Utero Exposure to Zika Virus Results in sex-Specific Memory Deficits and Neurological Alterations in Adult Mice
Thiago A Andrade1, Julia S Fahel1, Jessica M de Souza1
1Department of Biochemistry and Immunology, ICB, 28114Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.
ASN Neuro
|August 26, 2022
Summary Statement:
In utero exposure to ZIKV leads to decreased number of neurons in adult mice. Female mice exposed to ZIKV in utero exhibit lower levels of BDNF, a decrease in synaptic markers, memory deficits, and risk-taking behavior during adulthood.
