Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Management of Insomnia01:19

Management of Insomnia

314
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
314
Stages of Sleep01:22

Stages of Sleep

434
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
434
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

200
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
200
Understanding Sleep01:11

Understanding Sleep

466
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
466
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

212
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
212

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep Brain Stimulation for Sleep-Wake Regulation: A Narrative Review.

Stereotactic and functional neurosurgery·2026
Same author

Islet response to photobiomodulation varies with the nature of the stress: insights from hypoxia-reperfusion.

Lasers in medical science·2026
Same author

Inhibition of stress resilience and adult hippocampal neurogenesis by platelet-derived LPA16:0 in anxiety.

Nature communications·2026
Same author

Outdoor ground surface influences spatiotemporal parameters of walking for individuals undergoing rehabilitation: An observational study.

PloS one·2025
Same author

Impact of photobiomodulation on beta cells and Islets under stress conditions.

Acta diabetologica·2025
Same author

Red and near-infrared light treatment can change the intensity of biophoton emissions in cell culture.

Scientific reports·2025

Related Experiment Video

Updated: Aug 30, 2025

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases
07:56

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases

Published on: June 28, 2024

865

Lights at night: does photobiomodulation improve sleep?

Audrey Valverde1, Catherine Hamilton2, Cécile Moro1

  • 1Université Grenoble Alpes, FDD and CEA-LETI, Clinatec, Grenoble, France.

Neural Regeneration Research
|August 26, 2022
PubMed
Summary

New research explores photobiomodulation (PBM) as a non-drug therapy to improve sleep quality. Applying specific light wavelengths at night may enhance brain waste removal, boosting overall health and well-being.

Keywords:
aquaporin 4glymphhaticinfrarednon-pharmacologicalredsleep captranscranialwakefulness

More Related Videos

A Protocol for Transcranial Photobiomodulation Therapy in Mice
13:07

A Protocol for Transcranial Photobiomodulation Therapy in Mice

Published on: November 18, 2018

12.3K
Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
09:03

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

Published on: March 28, 2025

592

Related Experiment Videos

Last Updated: Aug 30, 2025

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases
07:56

Author Spotlight: Developing Photo-Stimulation Technology for Toxin Removal in Sleep-Related Brain Diseases

Published on: June 28, 2024

865
A Protocol for Transcranial Photobiomodulation Therapy in Mice
13:07

A Protocol for Transcranial Photobiomodulation Therapy in Mice

Published on: November 18, 2018

12.3K
Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
09:03

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

Published on: March 28, 2025

592

Area of Science:

  • Neuroscience
  • Sleep Science
  • Biotechnology

Background:

  • Sleep is vital for overall health, affecting cognitive functions and increasing the risk of neurodegenerative diseases when poor.
  • Many individuals struggle with sleep quality, impacting daily life and long-term health outcomes.

Purpose of the Study:

  • To review photobiomodulation (PBM) as a novel, non-pharmacological approach to enhance sleep quality.
  • To explore the potential of transcranial nocturnal PBM in improving brain function and sleep.

Main Methods:

  • Review of existing literature on photobiomodulation (PBM) and its effects on physiological processes.
  • Focus on studies utilizing specific light wavelengths applied to body tissues, particularly at night.
  • Examination of animal models demonstrating PBM's impact on brain waste clearance.

Main Results:

  • Photobiomodulation (PBM) involves applying specific light wavelengths to stimulate cellular activity.
  • Animal studies indicate that nocturnal PBM can enhance the brain's waste removal processes.
  • This suggests a potential mechanism for improving sleep quality through enhanced brain function.

Conclusions:

  • Transcranial nocturnal photobiomodulation (PBM) shows promise as a non-pharmacological treatment for improving sleep quality.
  • By enhancing the brain's house-keeping functions during sleep, PBM may contribute to better overall health and well-being.
  • Further research into PBM for sleep enhancement is warranted.