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Published on: September 13, 2019
Congenital sacrococcygeal rhabdomyosarcoma
Renuka Venkata Inuganti1, Amulya Boddapati1, Atchyuta Mathi1
1Department of Pathology, NRI Medical College, Guntur, Andhra Pradesh, India.
Insights
Rhabdomyosarcoma (RMS), a rare pediatric cancer, can present as a sacral nodule in infants. Histopathology confirmed RMS in a 4-month-old male, highlighting its varied presentation.
Area of Science:
- Pediatric Oncology
- Skeletal Muscle Tumors
Background:
- Rhabdomyosarcoma (RMS) is a malignant soft-tissue sarcoma originating from embryonic striated muscle precursors.
- It commonly affects pediatric patients, typically in the head-and-neck, genitourinary, or extremity regions.
Observation:
- A rare case of RMS presented in a 4-month-old male infant with a sacral nodule.
- The tumor's location was unusual, being in the sacrococcygeal area, which is rarely affected by RMS.
Findings:
- Histopathological examination and immunohistochemical marker studies confirmed the diagnosis of Rhabdomyosarcoma.
- No teratomatous elements were detected in the tumor, differentiating it from other sacral masses.
Implications:
- This case underscores the importance of considering RMS in the differential diagnosis of pediatric sacral masses.
- Early diagnosis and appropriate treatment are crucial for improving outcomes in pediatric soft-tissue sarcomas.
Abstract:
Rhabdomyosarcoma (RMS) is one of the common malignant soft-tissue sarcomas affecting children. It originates from the embryonic mesenchyme precursor of striated muscle and is frequently seen in the head-and-neck region, genitourinary system and extremities. Occasionally, it arises from the retroperitoneum, biliary tract and abdomen and is rarely seen in the sacrococcygeal area. A 4-month-male child presented with a nodule over the sacrum. Based on histopathology and immunohistochemical marker studies, a final diagnosis of RMS was rendered. There was no evidence of any teratomatous elements.
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