Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Term Evolution of Microstructure, Density, and Yield Strength of Pure Lead After Solidification Under Different Cooling Rates.

Materials (Basel, Switzerland)·2026
Same author

Effects of Partial Replacement of Wheat Bran with Poplar Wood Composite Fiber on Growth Performance, Nutrient Apparent Digestibility, Immune Function, and Gut Microbiota in Growing Pigs.

Veterinary sciences·2026
Same author

Extracellular vesicle-integrated gelatin sponges enhance angiogenesis and cell migration in wound healing.

Journal of materials chemistry. B·2026
Same author

The therapeutic potential of puerarin on diabetic kidney disease: Focus on molecular mechanisms and future perspectives.

Pharmacological research·2026
Same author

Longitudinal trends of per- and polyfluoroalkyl substances in Chinese children from birth to 7 years of age.

Environment international·2026
Same author

[Advances in targeted therapy for pulmonary arterial hypertension].

Zhonghua yi xue za zhi·2026
Same journal

Interfacial Behavior and Adsorption Mechanisms of Sorbitol Polyether Ester Emulsifiers in D-Phase Emulsion Systems: Applications for Spontaneous Emulsification.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Ti<sub>3</sub> Cluster-Doped 2D Goldene Surface for Electronic and Optical Sensing of Oxygen, Nitrogen, and Hydrocarbon-Based Respiratory Biomarkers: A DFT Study.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Condensation of GO<i>x</i> by Restoring Global Protein Fold on Diazo-Enriched SG Surfaces: Reinstallation of FADs Restores Biocatalytic Sustainability in Quantifying Blood Glucose.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Correction to "Protein Encapsulated DNA Metal Nanocluster as Fluorescent Nanoprobe for Detecting Insulin".

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Rational Design of V<sub>2</sub>O<sub>5</sub> Hierarchical Microspheres with Tunable Porosities and Primary Building Blocks for Enhanced Lithium Storage Performance.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Roles of Anion and Cation Doping in g-C<b><sub>3</sub></b>N<b><sub>4</sub></b> as Artificial SEI for Regulating Interfacial Zn<b><sup>2+</sup></b> Deposition in Aqueous Zinc Metal Anodes.

Langmuir : the ACS journal of surfaces and colloids·2026
See all related articles

Related Experiment Video

Updated: Aug 30, 2025

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping
14:58

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Published on: June 3, 2015

14.9K

Generating Lifetime-Enhanced Microbubbles by Decorating Shells with Silicon Quantum Nano-Dots Using a 3-Series

Bingjie Wu1, C J Luo1, Ashwin Palaniappan1

  • 1Department of Mechanical Engineering, University College London (UCL), London WC1E 7JE, U.K.

Langmuir : the ACS Journal of Surfaces and Colloids
|August 26, 2022
PubMed
Summary
This summary is machine-generated.

Stable, monodisperse microbubbles loaded with quantum dots and protein were created using a novel microfluidic device. This method enhances microbubble stability and allows for tailored size control for improved effectiveness.

More Related Videos

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)&#8211;Cell Interaction and the Resultant Bioeffects at the Single-cell Level
11:14

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Published on: January 10, 2017

11.8K
Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles
11:13

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Published on: March 13, 2016

10.8K

Related Experiment Videos

Last Updated: Aug 30, 2025

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping
14:58

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Published on: June 3, 2015

14.9K
A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)&#8211;Cell Interaction and the Resultant Bioeffects at the Single-cell Level
11:14

A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level

Published on: January 10, 2017

11.8K
Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles
11:13

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

Published on: March 13, 2016

10.8K

Area of Science:

  • Materials Science
  • Biotechnology
  • Microfluidics

Background:

  • Microbubble stability is critical for their application efficacy.
  • Controlling microbubble size and stability is a persistent challenge.

Purpose of the Study:

  • To develop a method for generating stable, monodisperse, quantum dot-loaded protein microbubbles.
  • To investigate the influence of microfluidic parameters on microbubble characteristics.
  • To create a predictive model for microbubble generation.

Main Methods:

  • Utilized a novel microfluidic device with serially connected T-junctions.
  • Generated bovine serum albumin (BSA) protein microbubbles loaded with silicon quantum dots (SiQDs).
  • Employed fluorescence microscopy for characterization and developed a computational model.

Main Results:

  • Successfully generated stable, monodisperse SiQD-loaded BSA microbubbles down to 22.8 ± 1.4 μm.
  • Demonstrated that microbubble diameter and stability can be precisely controlled by adjusting T-junction number, flow rate, and concentrations.
  • Observed increased microbubble lifetime with higher T-junction numbers and BSA/SiQD concentrations.
  • Computational model accurately predicted experimental microbubble diameter and stability.

Conclusions:

  • A new route for producing stable, well-characterized protein and quantum dot-loaded microbubbles was established.
  • The triple T-junction microfluidic system offers enhanced control over microbubble properties.
  • This approach holds potential for advanced applications requiring stable, functionalized microbubbles.