Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Angular deformity of the lower extremity: evaluation with quantitative bone scintigraphy. Work in progress.

H T Harcke, S E Zapf, G A Mandell

    Radiology
    |August 1, 1987
    PubMed
    Summary

    A new method quantifies knee growth plate changes using scintigraphy ratios. This technique aids in diagnosing varus or valgus deformities and monitoring growth post-injury.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Vital Signs: Health Care-Associated Legionnaires' Disease Surveillance Data From 20 States and a Large Metropolitan Area-United States, 2015.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2017
    Same author

    Bone mineral density in MPS IV A (Morquio syndrome type A).

    Molecular genetics and metabolism·2015
    Same author

    Physician Scientist Training in the United States: A Survey of the Current Literature.

    Evaluation & the health professions·2014
    Same author

    Tobacco control in Vietnam.

    Public health·2013
    Same author

    The contribution of international medical students to Taiwanese medical school classes.

    Medical teacher·2012
    Same author

    Common and expected postmortem CT observations involving the brain: mimics of antemortem pathology.

    AJNR. American journal of neuroradiology·2012

    Area of Science:

    • Orthopedics
    • Pediatric Radiology
    • Medical Imaging Analysis

    Background:

    • Angular deformities of the knee, such as varus and valgus, are common in children.
    • Accurate assessment of growth plate (physis) activity is crucial for managing these conditions.
    • Existing methods for evaluating physeal growth may lack quantitative precision.

    Purpose of the Study:

    • To develop and validate a quantitative technique for analyzing distal femoral and proximal tibial growth plates.
    • To assess the utility of this technique in differentiating between varus and valgus knee deformities.
    • To explore its potential for monitoring skeletal growth after trauma or infection.

    Main Methods:

    • Development of a computer-generated region of interest (ROI) placement strategy on magnification scintigraphs.

    Related Experiment Videos

  • Division of distal femoral and proximal tibial physes into four equal segments for analysis.
  • Calculation of the ratio of radioactive counts in the medial versus lateral halves of the physes in 34 children (23 healthy, 11 with deformity).

    • Main Results:

    • Established normal count ratios for healthy femurs (0.74-0.98) and tibias (0.98-1.20).
    • Demonstrated a significant correlation between above-normal ratios and valgus deformity.
    • Showed a significant correlation between below-normal ratios and varus deformity.

    Conclusions:

    • The developed scintigraphy-based technique provides a quantitative measure of knee physeal growth.
    • This method effectively distinguishes between varus and valgus knee deformities.
    • It holds promise as a tool for monitoring growth plate status following pediatric knee trauma or infection.