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Updated: Aug 30, 2025
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
MULTIMODAL IMAGING OF UNILATERAL IDIOPATHIC MACULAR TELANGIECTASIA TYPE 2: A FIVE-YEAR STUDY
George J Manayath1, Shishir Verghese, Venkatapathy Narendran
1Department of Retina and Vitreous Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India.
Purpose:
To report a rare presentation of unilateral macular telangiectasia Type 2 followed up over 5 years.
Methods:
Case report.
Results:
A 58-year-old man presented to us with complaints of painless progressive reduction of vision in the right eye for the past 2 years. He had no systemic illnesses. On examination, his best corrected visual acuity was 20/40 in the right eye and 20/20 in the left eye. Fundus examination in the right eye revealed loss of foveal reflex along with mild temporal graying of the fovea, and the left eye revealed results within the normal limits. Both eyes showed the presence of peripapillary myelinated nerve fibers. Multimodal imaging findings included spectral-domain optical coherence tomography, optical coherence tomography angiography, fundus autofluorescence, and fundus fluorescein angiogram, which revealed findings suggestive of exudative preproliferative variant of Mac-Tel 2 in the right eye, whereas the left eye was showed results within normal limits. After a follow-up of 5 years, spectral-domain optical coherence tomography and optical coherence tomography angiography revealed no striking differences in both eyes, with no evidence of the disease in his left eye.
Conclusion:
This report highlights a rare advanced unilateral presentation of Mac-Tel 2 with no evidence of even early signs of the disease in the fellow eye, over a long-term follow-up.
