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Elabela Peptide: An Emerging Target in Therapeutics.
Maneesha Sharma1, Kedar S Prabhavalkar1, Lokesh Kumar Bhatt1
1Department of Pharmacology, SVKM's Dr. Bhanuben Nanavati College of Pharmacy, Vile Parle (W), Mumbai, India.
Current Drug Targets
|August 27, 2022
Summary
Elabela is a peptide hormone involved in blood pressure and heart development. This review explores its physiological roles and implications in diseases like heart failure and cancer.
Area of Science:
- Biochemistry
- Physiology
- Molecular Biology
Background:
- Elabela is the second endogenous ligand identified for the Apelin receptor.
- This bioactive micropeptide is distributed across various tissues and organs.
- It plays a crucial role in numerous physiological functions.
Conclusions:
- Elabela is a significant bioactive peptide with broad physiological and pathological relevance.
- Understanding Elabela's functions is crucial for developing new therapeutic strategies.
- Elabela represents a promising target for treating cardiovascular, oncological, and neurological diseases.
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