Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Psychosocial issues.

M J Goldstein

    Schizophrenia Bulletin
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Schizophrenia vulnerability may appear in childhood, influenced by family stress. Family interventions alongside medication can reduce relapse risk by improving the home environment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pretransplant CD4 Count Influences Immune Reconstitution and Risk of Infectious Complications in Human Immunodeficiency Virus-Infected Kidney Allograft Recipients.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2016
    Same author

    Glutathione S-transferase iso-enzymes in perfusate from pumped kidneys are associated with delayed graft function.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2014
    Same author

    Family factors associated with schizophrenia and anorexia nervosa.

    Journal of youth and adolescence·2013
    Same author

    Case report: parenchymal pseudoaneurysm of a renal allograft after core needle biopsy: a rare cause of allograft injury.

    Transplantation proceedings·2011
    Same author

    Randomised clinical trial: a novel rabeprazole extended release 50 mg formulation vs. esomeprazole 40 mg in healing of moderate-to-severe erosive oesophagitis - the results of two double-blind studies.

    Alimentary pharmacology & therapeutics·2010
    Same author

    Optimized technique in needle biopsy protocol shown to be of greater sensitivity and accuracy compared to wedge biopsy.

    Transplantation proceedings·2010
    Same journal

    The Effect of Semaglutide on Antipsychotic-Induced Weight Gain and Other Metabolic Parameters, among a Cohort of Inpatients.

    Schizophrenia bulletin·2026
    Same journal

    Longitudinal Impact of Birthweight and its Polygenic Risk Score on Glucose and Antipsychotic-Induced Weight Gain in First Episode Psychosis.

    Schizophrenia bulletin·2026
    Same journal

    The Key to Clozapine Mystery May Lie in its Shape.

    Schizophrenia bulletin·2026
    Same journal

    Absolute Receptor Occupancy, Not Rate of Decline, Predicts Relapse.

    Schizophrenia bulletin·2026
    Same journal

    Does Sex Affect Antipsychotic-Induced Weight Gain in Patients Being Treated for Psychotic Disorders: A Systematic Review and Meta-analysis.

    Schizophrenia bulletin·2026
    Same journal

    Blunted experience of pleasure, unsystematic subjective value representation, and disrupted goal-directed behaviors: an ecological momentary assessment study across mood and psychotic disorders.

    Schizophrenia bulletin·2026
    See all related articles

    Area of Science:

    • Psychiatry
    • Developmental Psychology
    • Behavioral Science

    Background:

    • Schizophrenia's etiology is complex, involving genetic vulnerability and environmental stressors.
    • The vulnerability-stress model provides a framework for understanding schizophrenia's development.
    • Early identification of vulnerability markers is crucial for intervention.

    Purpose of the Study:

    • To examine psychosocial factors influencing schizophrenia onset, course, and treatment.
    • To review evidence for childhood vulnerability markers and family stress.
    • To assess the impact of family-based interventions on schizophrenia relapse.

    Main Methods:

    • Review of high-risk studies focusing on offspring of parents with schizophrenia.
    • Analysis of the vulnerability-stress model in relation to schizophrenia.

    Related Experiment Videos

  • Examination of family dynamics, expressed emotion (EE), and intervention outcomes.

    • Main Results:

    • Vulnerability signs may emerge in childhood (neuromotor, attentional, social behavior), but specificity is unclear.
    • Stressful family relationships may potentiate schizophrenia in vulnerable individuals.
    • High expressed emotion (EE) is linked to relapse, potentially related to time to first hospitalization.

    Conclusions:

    • Psychosocial factors, including family environment, play a significant role in schizophrenia.
    • Family-based interventions, combined with antipsychotic treatment, show short-term efficacy in reducing relapse.
    • Reducing negative family affective climate is a key mechanism for intervention success.