Related Experiment Video
Updated: Aug 30, 2025

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
Published on: July 3, 2014
The effect of using virtual bolus on VMAT plan quality for left-sided breast cancer patients
Tugrul Berat Ugurlu1, Canan Koksal Akbaş2, Kamuran Ibis3
1Istanbul University Institute of Health Sciences, Medical Physics Department, Istanbul, Turkey.
Abstract:
In breast cancer radiotherapy treatment with Volumetric Modulated Arc Therapy (VMAT), the respiratory motion may lead to underdosing of the target and overdosing of critical organs such as the heart and lungs. This study aims to investigate the effect of using Virtual Bolus with different thicknesses on VMAT plan quality for patients with 20 advanced left-sided breast cancers. The result of the study showed that using Virtual Bolus for VMAT treatment planning is a viable method to avoid any missing target coverage.
Related Concept Videos
Two-Compartment Open Model: IV Bolus Administration
The disparity between drug input and the sum of drug transfer rates between...
One-Compartment Open Model for IV Bolus Administration: General Considerations
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...

