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Primary thyroid chondrosarcoma: a case report of an extremely rare malignancy
Shadi Awny1, Mohammad Zuhdy1, Omar Hamdy1
1Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt.
Journal of the Egyptian National Cancer Institute
|August 28, 2022
Summary
Primary thyroid chondrosarcoma is an extremely rare malignancy. Early diagnosis and surgical treatment are crucial for this aggressive cancer, despite a poor prognosis.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Differentiated thyroid carcinomas constitute approximately 90% of thyroid malignancies.
- Non-epithelial thyroid malignancies, such as lymphomas and sarcomas, are rare, accounting for 0.01% to 1.5% of cases.
Observation:
- A case of primary thyroid chondrosarcoma is presented in a 79-year-old female patient.
- The patient presented with a hard thyroid swelling, diagnosed via histopathological assessment.
Findings:
- Chondrosarcoma of the thyroid gland is exceptionally rare in both primary and metastatic forms.
- This case highlights an extremely rare instance of thyroid chondrosarcoma.
Implications:
- Early and prompt diagnosis is essential for managing thyroid chondrosarcoma.
- Surgical intervention is the primary treatment modality for this rare thyroid cancer, despite its generally poor prognosis.

