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MicroRNAs

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...

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Related Experiment Video

Updated: Aug 30, 2025

High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs

High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs

Published on: August 3, 2011

Multiplex microRNA detection

¹Department of Chemistry, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan. yusuke.sato.a7@tohoku.ac.jp.

Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry

|August 28, 2022

Summary

No abstract available in PubMed .

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