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Updated: Aug 30, 2025
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Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
14.5K
Advances in microneedles for non-transdermal applications
Xiaona Cao1,2,3, Guojun Chen1,2
1Department of Biomedical Engineering, McGill University, Montreal, Quebec, Canada.
Expert Opinion on Drug Delivery
|August 29, 2022
Summary
Microneedles (MNs) are advancing beyond skin applications into diverse non-transdermal uses. This technology promises more efficient drug delivery for ocular, vascular, and cancer treatments.
Area of Science:
- Biomedical Engineering
- Materials Science
- Drug Delivery Systems
Background:
- Microneedles (MNs) are established for transdermal applications.
- Advances in materials science and microfabrication enable new MN uses.
- Clinical devices are expanding MN capabilities.
Purpose of the Study:
- To review recent advances in microneedle technology for non-transdermal applications.
- To classify MNs and highlight their use in ocular, vascular, oral, mucosal, and cancer tissues.
Main Methods:
- Literature review of microneedle technology.
- Classification of microneedle designs and applications.
- Analysis of recent research in non-transdermal microneedle use.
Main Results:
- Microneedle designs have been broadened for numerous non-transdermal applications.
- Specific applications include ocular, vascular, oral, mucosal, and cancer tissues.
- Potential for high drug delivery efficiency exceeding traditional methods.
Conclusions:
- Microneedle technology is expanding into diverse non-transdermal fields.
- Advancements in MN systems can enhance drug delivery efficiency.
- Translation and commercialization are critical for novel microneedle technologies.
