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Total Joint Arthroplasty in Patients With Atrial Septal Defects: What Are the 90-Day Complications?
Jennifer Bido1, Simarjeet Puri1, Eduardo A Salvati1
1Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.
Insights
Patients with atrial septal defects (ASDs) or patent foramen ovale (PFO) undergoing hip or knee arthroplasty had no embolic events. A cardiology evaluation before surgery is recommended to assess risks and benefits.
Area of Science:
- Orthopedic Surgery
- Cardiology
- Vascular Surgery
Background:
- Congenital heart defects like atrial septal defects (ASDs) and patent foramen ovale (PFO) may elevate embolic event risk during total hip or knee arthroplasty (THA/TKA).
- Understanding this risk is crucial for patient management and surgical planning.
Purpose of the Study:
- To determine the 90-day incidence of embolic events and other complications in patients with ASD/PFO undergoing primary THA/TKA.
- To evaluate the safety of THA/TKA in patients with known cardiac defects.
Main Methods:
- Retrospective review of 160 patients (196 primary arthroplasties) with ASD/PFO.
- Data collected on patient demographics, preoperative anticoagulation, and postoperative complications within 90 days.
- Follow-up averaged 19 months.
Main Results:
- No embolic events were identified in the study cohort.
- Seven percent (14 patients) experienced complications, including bleeding (3%) and other nonoperative issues (8%).
- Three patients required reoperation for periprosthetic fractures (2) or infection (1).
Conclusions:
- Primary THA/TKA in patients with ASD/PFO did not result in embolic events in this cohort.
- Preoperative cardiology evaluation is recommended to assess risks, benefits, and potential defect repair to mitigate embolic event risk.
Background:
Congenital heart defects, such as atrial septal defects (ASDs) and patent foramen ovale (PFO), may increase the risk of embolic events in total hip or knee arthroplasty (THA/TKA). The objective of this study was to determine the 90-day incidence of intraoperative and postoperative embolic events and all other complications in patients with a known ASD/PFO who underwent primary hip and knee arthroplasty.
Methods:
This is a retrospective review of 160 patients with ASD/PFO undergoing 196 primary arthroplasties (94 THAs, 102 TKAs) at a single institution. The mean age was 64 years (standard deviation [SD] 11.1), 40.6% were male, and average body mass index was 31 kg/m2 (SD 7.2). The mean follow-up period was 19 months (SD 16). Forty-three percent of patients were on anticoagulation preoperatively. All patients received postoperative thromboprophylaxis (48% aspirin, 31% direct oral anticoagulants, 18% warfarin, 3% enoxaparin).
Results:
There were no embolic events identified. Fourteen patients (7%) developed complications within 90 days. Three had bleeding complications, and 8 had other nonoperative complications, which were all managed conservatively and had uneventful recoveries. Additionally, 3 patients had complications requiring reoperations: 2 for periprosthetic fractures (1 THA, 1 TKA) and 1 for a periprosthetic infection (TKA).
Conclusions:
In this cohort of patients with a known ASD/PFO undergoing THAs and TKAs, there were no cases of embolic events. However, it would be advisable to have a thorough cardiology evaluation to assess potential risks and benefits of defect repair prior to total joint arthroplasty and to reduce the risk of paradoxical embolic events and the necessity of potent anticoagulation.
Level Of Evidence:
Prognostic Level IV.
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