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Author Spotlight: A Stable Phantom Material for Optical and Acoustic Imaging
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Anthropomorphic Polydimethylsiloxane silicone-based phantom for Diffuse Optical Imaging.

M V Waks Serra1, V Noseda Grau2, D A Vera1

  • 1CIFICEN (UNCPBA - CICPBA - CONICET), Pinto 399, 7000, Tandil, Argentina.

Heliyon
|August 29, 2022
PubMed
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Researchers developed anthropomorphic breast phantoms using silicone for diffuse optical mammography. These phantoms accurately mimic human breast properties, aiding in the performance testing of optical imaging devices.

Area of Science:

  • Biomedical Engineering
  • Medical Imaging Physics

Background:

  • Diffuse optical mammography requires realistic breast phantoms for accurate device calibration and performance evaluation.
  • Existing phantoms may not fully replicate the complex optical and mechanical properties of human breast tissue.

Purpose of the Study:

  • To develop and characterize anthropomorphic breast phantoms with tunable optical and mechanical properties.
  • To evaluate the suitability of these phantoms for testing diffuse optical imaging systems.

Main Methods:

  • Phantoms constructed using Polydimethylsiloxane (PDMS) silicones with varying concentrations of scattering and absorbing agents.
  • Mechanical properties adjusted by incorporating silicone fluid.
  • Optical properties characterized by measuring scattering and absorption coefficients.
Keywords:
Diffuse optical imagingMammographyPDMS phantom

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  • Performance validated using diffuse optical imaging experiments and comparison with ultrasound.

    • Main Results:

    • The PDMS phantoms successfully replicated the optical and mechanical properties of human breasts.
    • An alternative, easier-to-handle scattering agent was identified.
    • Diffuse optical imaging experiments demonstrated the phantoms' utility in simulating breast tumors with inclusions.

    Conclusions:

    • The developed anthropomorphic phantoms are suitable for calibrating and testing diffuse optical mammography devices.
    • These phantoms offer a valuable tool for advancing near-infrared optical imaging in breast cancer detection.