Lymphocytic hypophysitis

A patient with a chronic lymphocytic hypophysitis (LYHY) following an idiopathic lymphocytic meningitis is described. Computed tomography scan of the sella turcica suggested a pituitary adenoma with suprasellar extension, whereas hormonal investigations showed a functional lesion at the suprapituitary level. A transsphenoidal biopsy revealed diffuse lymphocytic infiltration of the adenohypophysis without characteristics of a sarcoid lesion. The possible relationship between idiopathic (viral?) lymphocytic meningitis and LYHY is discussed.