Multiple myeloma and its ocular manifestations
Survey of Ophthalmology
|March 1, 1987
Summary
Multiple myeloma, a cancer of immune cells, often affects the eyes. This review details the systemic and ocular manifestations of this condition, including common ciliary body cysts and retinal vascular issues.
Area of Science:
- Ophthalmology
- Hematology
- Immunology
Background:
- Multiple myeloma is a plasma cell malignancy impacting the immune system.
- Ocular involvement is a frequent, yet often under-recognized, complication of multiple myeloma.
- Understanding the spectrum of eye conditions associated with multiple myeloma is crucial for patient care.
Purpose of the Study:
- To review the systemic and immunologic features of multiple myeloma.
- To illustrate the diverse ocular manifestations observed in multiple myeloma patients.
- To enhance awareness among clinicians regarding the ophthalmic complications of this hematologic malignancy.
Main Methods:
- Literature review of systemic and ocular findings in multiple myeloma.
- Compilation of reported frequencies of ocular manifestations.
- Illustration of common and uncommon ocular presentations.
Main Results:
- Ciliary body cysts occur in 33-50% of multiple myeloma patients.
- Retinal vascular lesions are reported in up to 66% of cases.
- Corneal and orbital involvement are less frequent but documented.
Conclusions:
- Ocular manifestations are common in multiple myeloma, ranging from vascular lesions to cysts.
- Early recognition of eye symptoms can aid in the diagnosis and management of multiple myeloma.
- This review highlights the importance of a multidisciplinary approach in managing patients with multiple myeloma and ocular complications.
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