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Related Experiment Videos

Multiple myeloma and its ocular manifestations.

A J Knapp, S Gartner, P Henkind

    Survey of Ophthalmology
    |March 1, 1987
    PubMed
    Summary

    Multiple myeloma, a cancer of immune cells, often affects the eyes. This review details the systemic and ocular manifestations of this condition, including common ciliary body cysts and retinal vascular issues.

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    Area of Science:

    • Ophthalmology
    • Hematology
    • Immunology

    Background:

    • Multiple myeloma is a plasma cell malignancy impacting the immune system.
    • Ocular involvement is a frequent, yet often under-recognized, complication of multiple myeloma.
    • Understanding the spectrum of eye conditions associated with multiple myeloma is crucial for patient care.

    Purpose of the Study:

    • To review the systemic and immunologic features of multiple myeloma.
    • To illustrate the diverse ocular manifestations observed in multiple myeloma patients.
    • To enhance awareness among clinicians regarding the ophthalmic complications of this hematologic malignancy.

    Main Methods:

    • Literature review of systemic and ocular findings in multiple myeloma.
    • Compilation of reported frequencies of ocular manifestations.
    • Illustration of common and uncommon ocular presentations.

    Main Results:

    • Ciliary body cysts occur in 33-50% of multiple myeloma patients.
    • Retinal vascular lesions are reported in up to 66% of cases.
    • Corneal and orbital involvement are less frequent but documented.

    Conclusions:

    • Ocular manifestations are common in multiple myeloma, ranging from vascular lesions to cysts.
    • Early recognition of eye symptoms can aid in the diagnosis and management of multiple myeloma.
    • This review highlights the importance of a multidisciplinary approach in managing patients with multiple myeloma and ocular complications.

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