Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

19.7K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
19.7K
What is Genetic Engineering?00:49

What is Genetic Engineering?

75.0K
Overview
75.0K
The Central Dogma01:20

The Central Dogma

24.6K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
24.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The convergence of AI and synthetic biology: the looming deluge.

npj biomedical innovations·2026
Same author

Characterisation of the SNAP-25 and SNAP-23 cleavage properties of the botulinum neurotoxin-like protein from Enterococcus.

Journal of neural transmission (Vienna, Austria : 1996)·2025
Same author

Toward a framework for risk mitigation of potential misuse of artificial intelligence in biomedical research.

Nature machine intelligence·2025
Same author

Mapping variation in dual use risk assessments of synthetic biology projects.

Frontiers in bioengineering and biotechnology·2025
Same author

Unmet Expectations: Life Scientists' Views on Biorisk and Responsibility.

Applied biosafety : journal of the American Biological Safety Association·2025
Same author

Probing the properties of PTEN specific botulinum toxin type E mutants.

Journal of neural transmission (Vienna, Austria : 1996)·2025

Related Experiment Video

Updated: Aug 30, 2025

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

12.5K

Developing a Comprehensive, Adaptive, and International Biosafety and Biosecurity Program for Advanced Biotechnology:

Piers Millett1, Thomas Binz2, Sam Weiss Evans3

  • 1iGEM Foundation, Cambridge, MA, USA.

Applied Biosafety : Journal of the American Biological Safety Association
|August 29, 2022
PubMed
Summary

The international synthetic biology competition iGEM has a robust biosafety and biosecurity program that evolves with new technologies and risks. This adaptive approach ensures comprehensive safety throughout project lifecycles.

Keywords:
adaptive biosafetybiological engineeringbiotechnologygenetic engineeringiGEMsynthetic biology

More Related Videos

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches
10:07

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Published on: October 8, 2021

1.5K
Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
10:17

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience

Published on: November 15, 2024

1.1K

Related Experiment Videos

Last Updated: Aug 30, 2025

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

12.5K
Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches
10:07

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Published on: October 8, 2021

1.5K
Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
10:17

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience

Published on: November 15, 2024

1.1K

Area of Science:

  • Synthetic biology
  • Biosafety and biosecurity
  • Risk management

Background:

  • The international Genetically Engineered Machines (iGEM) competition has established a dedicated biosafety and biosecurity program.
  • This program addresses both traditional pathogen-based and emerging risks associated with new technologies in synthetic biology.

Purpose of the Study:

  • To review specific elements of the iGEM biosafety and biosecurity program.
  • To illustrate how program implementation has improved policy and risk management strategies.
  • To assess the program's adaptability to technical advancements and diverse genetic resources.

Main Methods:

  • Review of iGEM's biosafety and biosecurity program elements.
  • Analysis of concrete examples of program implementation and policy impact.
  • Examination of risk assessment tools and community roles throughout project lifecycles.

Main Results:

  • The iGEM program is forward-leaning, addressing traditional and emerging risks.
  • It integrates biosafety and biosecurity into the competition's technical work and project lifecycle.
  • Specific tools aid in risk recognition, management, and identification of gaps.

Conclusions:

  • iGEM's adaptive risk management approach has resulted in a comprehensive, cross-cutting biosafety and biosecurity program.
  • The program effectively covers the entire lifecycle of synthetic biology projects.
  • Continuous adaptation enhances the program's efficacy in managing diverse risks.