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Hypertension in Women: A South-Asian Perspective

Fatima Farrukh1, Amin Abbasi1, Misbah Jawed2

  • 1Medical College, Aga Khan University, Karachi, Pakistan.

Frontiers in Cardiovascular Medicine
|August 29, 2022
PubMed

Insights

Hypertension control remains suboptimal in women, influenced by sex-specific factors like age and oral contraceptives. Further research is needed for tailored treatments to reduce cardiovascular disease risk.

Area of Science:

  • Cardiology
  • Endocrinology
  • Pharmacology

Background:

  • Hypertension significantly contributes to cardiovascular disease morbidity and mortality.
  • Despite its impact, hypertension treatment and control are suboptimal in both men and women.
  • Sex-specific factors influence hypertension development and management, particularly in women.

Purpose of the Study:

  • To review the current understanding of hypertension in women.
  • To highlight sex-specific factors contributing to hypertension.
  • To discuss challenges and considerations in antihypertensive drug choices for women.

Main Methods:

  • A narrative review was conducted.
  • Relevant studies were identified through searches of databases like PubMed and ScienceDirect.
  • Findings from pertinent articles were summarized and integrated.

Main Results:

  • Sex-specific factors, including age, combined oral contraceptives (COCs), polycystic ovarian syndrome (PCOS), and preeclampsia, are associated with hypertension development in women.
  • There are unique considerations for antihypertensive drug selection in women.
  • Medical treatment and adherence present unique challenges for South Asian women due to socio-cultural-economic factors.

Conclusions:

  • Hypertension control in women remains a significant challenge.
  • Optimal sex-specific treatment strategies are needed to improve hypertension control.
  • Further research is warranted to reduce cardiovascular disease risk in both genders through improved hypertension management.
Abstract

Keywords:
South Asiagendergender-specific differenceshypertensionsex-specificwomen

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