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Ketamine Infusions Administered Solely by Psychiatric Staff.

Muaid Ithman1, Robert Sobule2, Carolyn Kundert3

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Psychiatric teams can safely administer ketamine infusions for depression treatment. This pilot program at MUPC demonstrates efficacy without anesthesia specialists, offering a new approach for treatment-resistant depression.

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Area of Science:

  • Psychiatry
  • Pharmacology

Background:

  • Intravenous ketamine shows antidepressant effects for treatment-resistant depression.
  • Clinical use is increasing, often involving collaboration between anesthesia and psychiatry.
  • No prior reports exist on psychiatric teams solely administering ketamine infusions in hospitals.

Purpose of the Study:

  • To investigate the feasibility and safety of ketamine infusions administered by a psychiatric team.
  • To explore ketamine as a clinical intervention within a psychiatric hospital setting, independent of anesthesia specialists.

Main Methods:

  • A psychiatric-based ketamine infusion team was formed at Missouri University Psychiatric Center (MUPC).
  • The team, composed of mental health clinicians and staff, administered ketamine infusions.
  • This pilot program focused on clinical application within an acute mental inpatient facility.

Main Results:

  • Ketamine infusions were administered by a solely psychiatric-based team.
  • The MUPC team demonstrated that ketamine infusions can be a safe and effective intervention.
  • This approach was achieved without the need for collaboration with anesthesia specialists.

Conclusions:

  • Ketamine infusions can be safely and effectively administered by psychiatric teams in a hospital setting.
  • This model provides a novel intervention for treatment-resistant depression.
  • Collaboration with anesthesia specialists is not essential for ketamine infusion therapy in this context.