Related Experiment Video

Updated: Aug 30, 2025

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

529

Risk Factors of Delirium in Children in Pediatric Intensive Care Unit

Bhavesh Motwani1, Umesh Pandwar2, Amit Agrawal1

  • 1Department of Pediatrics, Gandhi Medical College and Kamla Nehru Hospital, Bhopal, Madhya Pradesh.

Indian Pediatrics
|August 29, 2022
PubMed

Insights

Delirium affects 20.2% of children in the Pediatric Intensive Care Unit (PICU). Key risk factors include respiratory failure and benzodiazepine use, highlighting the need for early detection in critically ill children.

Area of Science:

  • Pediatric Critical Care Medicine
  • Neuroscience
  • Psychiatry

Background:

  • Delirium is a common yet often unrecognized complication in critically ill children.
  • Understanding the prevalence and risk factors for pediatric delirium is crucial for effective management.
  • Pediatric Intensive Care Units (PICUs) present unique challenges for delirium assessment and treatment.

Purpose of the Study:

  • To determine the prevalence of delirium in children admitted to a Pediatric Intensive Care Unit (PICU).
  • To identify statistically significant risk factors associated with the development of delirium in this population.
  • To analyze the impact of delirium on the length of PICU stay.

Main Methods:

  • A 12-month descriptive study involving daily screening of consecutive PICU admissions for delirium using the Cornell Assessment of Pediatric Delirium (CAPD) score.
  • Collection and analysis of treatment-related and demographic variables.
  • Multivariable logistic regression was employed to identify independent risk factors for delirium.

Main Results:

  • Delirium was identified in 96 out of 476 screened patients, representing a prevalence of 20.2%.
  • Independent risk factors significantly associated with delirium included respiratory failure (P<0.001) and the administration of benzodiazepines (P<0.001).
  • The presence of multiple (≥2) risk factors also independently predicted delirium (P<0.001), and delirious patients had a significantly longer PICU stay (P<0.001).

Conclusions:

  • Delirium is a frequent complication in critically ill children admitted to the PICU.
  • Respiratory failure and benzodiazepine use are significant independent risk factors for pediatric delirium.
  • Early recognition and targeted management strategies are essential for improving outcomes in delirious pediatric patients.
Abstract

More Related Videos

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.3K
Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

2.8K

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
171
Intellectual Disability01:29

Intellectual Disability

Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
144
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
310
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
179
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
205
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
287