Acute Myeloid Leukemia: Challenges in Delivering End-of-Life Care
Vani Koets1, Marcos Montagnini2
1Hospice and Palliative Medicine, Spectrum Health Medical Group, Grand Rapids, MI, USA.
Patients with Acute Myeloid Leukemia (AML) face significant end-of-life (EOL) challenges, including symptom burden and underutilized palliative care. This case highlights the complexities of balancing patient autonomy with blood transfusions near EOL.
Area of Science:
- Hematology
- Palliative Care
- Oncology
Background:
- Acute Myeloid Leukemia (AML) presents a complex trajectory with high symptom burden and frequent end-of-life (EOL) hospitalizations.
- Palliative and hospice care remain underutilized in AML patients despite their poor prognosis.
Observation:
- Clinicians face challenges managing end-stage AML, particularly concerning blood product administration near EOL.
- A case illustrates patient and caregiver distress stemming from transfusion desires in end-stage AML.
Findings:
- Frequent chemotherapy use near EOL is common in AML.
- Blood product administration near EOL presents ethical and clinical dilemmas.
Implications:
- Optimal EOL care for AML requires balancing patient autonomy with potentially inappropriate interventions like transfusions.
- Effective communication and interdisciplinary collaboration are crucial for managing complex EOL care in AML patients.
More Related Videos
07:38Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
Published on: June 6, 2025
09:01Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Related Concept Videos
Ethical Issues
Ethical Concerns in Healthcare:
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Ethical Dilemmas II
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Endocarditis IV: Nursing Management
