Haemolysis with Mediterranean spotted fever and glucose-6-phosphate dehydrogenase deficiency

Mediterranean spotted fever with haemolysis is reported in a glucose-6-phosphate dehydrogenase deficient Algerian man. The clinical course was unusually severe for a 27-year-old patient. The authors suspect G6PD deficiency to be a cause of enhanced severity in Mediterranean spotted fever as well as in other rickettsioses.