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Frozen maternal platelets for neonatal thrombocytopenia
A case is reported of an alloimmunized, neonatal, thrombocytopenic patient who was successfully transfused with maternal platelets collected by cytapheresis and cryopreserved 3 months before delivery. Phlebotomy or cytapheresis of the mother immediately before delivery was avoided. Transfusion of maternal platelets over a 7-day period with aliquots containing an average of 7.1 X 10(10) platelets in 50 ml of plasma was possible. Satisfactory increases in platelet counts were sustained after transfusion.
A case is reported of an alloimmunized, neonatal, thrombocytopenic patient who was successfully transfused with maternal platelets collected by cytapheresis and cryopreserved 3 months before delivery. Phlebotomy or cytapheresis of the mother immediately before delivery was avoided. Transfusion of maternal platelets over a 7-day period with aliquots containing an average of 7.1 X 10(10) platelets in 50 ml of plasma was possible. Satisfactory increases in platelet counts were sustained after transfusion.