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Updated: Aug 30, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
Synthesis of 1,2-Diamines from Vinyl Sulfonium Salts and Arylamines
Cheng Wang1, Biao Liu1, Zeyu Shao1
1School of Life Science and Health Engineering, Jiangnan University, Wuxi, Jiangsu 214122, P. R. China.
Abstract:
A procedure for the synthesis of 1,2-diamines from vinyl sulfonium salts and arylamines under mild conditions was developed. This present synthetic protocol not only obviates the need for a transition-metal catalyst and an oxidizing reagent but also features a broad substrates scope. The practicability of this protocol is demonstrated by the one-pot synthesis, a scale-up reaction, and transformations of the products to diverse N-heterocyclic compounds. Mechanistic studies indicate that the formation of aziridine plays a key role during this diamination process.
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