Related Experiment Video
Updated: Aug 30, 2025

In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
Best Practice Guidelines for Surgical Site Infection in High-risk Pediatric Spine Surgery: Definition, Prevention,
Daniel Badin1, Christopher R Leland1, Hiroko Matsumoto2
1Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, MD.
Insights
Updated best practice guidelines were developed for pediatric spine surgery to reduce surgical site infections (SSI). These guidelines address high-risk patient identification, prevention, diagnosis, and treatment, aiming to standardize care and lower SSI incidence.
Area of Science:
- Pediatric Surgery
- Infectious Disease Control
- Clinical Practice Guidelines
Background:
- Existing best practice guidelines (BPG) for surgical site infection (SSI) lack consensus on high-risk patient identification, diagnosis, and treatment in pediatric spine surgery.
- Significant variability in clinical practice persists despite prior BPGs.
Purpose of the Study:
- To develop updated, consensus-based BPGs for pediatric spine surgery.
- To define high-risk patients for SSI and establish standardized protocols for prevention, diagnosis, and treatment.
Main Methods:
- Systematic literature review followed by a Delphi process involving 21 pediatric spine surgeons.
- Iterative electronic surveys, a live discussion session, and private voting were used to achieve consensus.
- Agreement of ≥70% was required for consensus, with revisions made to achieve agreement.
Main Results:
- Consensus was achieved on 17 items for defining high-SSI risk, 17 for prevention, 6 for diagnosis, and 9 for treatment in high-risk pediatric spine surgery patients.
- All 21 experts agreed to the publication and implementation of the developed guidelines.
Conclusions:
- Updated consensus-based BPGs are presented for high-risk pediatric spine surgery, covering SSI risk definition, prevention, diagnosis, and treatment.
- These guidelines aim to reduce practice variability and decrease the incidence of SSI in this patient population.
Background:
Prior "best practice guidelines" (BPG) have identified strategies to reduce the risk of acute deep surgical site infection (SSI), but there still exists large variability in practice. Further, there is still no consensus on which patients are "high risk" for SSI and how SSI should be diagnosed or treated in pediatric spine surgery. We sought to develop an updated, consensus-based BPG informed by available literature and expert opinion on defining high-SSI risk in pediatric spine surgery and on prevention, diagnosis, and treatment of SSI in this high-risk population.
Materials And Methods:
After a systematic review of the literature, an expert panel of 21 pediatric spine surgeons was selected from the Harms Study Group based on extensive experience in the field of pediatric spine surgery. Using the Delphi process and iterative survey rounds, the expert panel was surveyed for current practices, presented with the systematic review, given the opportunity to voice opinions through a live discussion session and asked to vote regarding preferences privately. Two survey rounds were conducted electronically, after which a live conference was held to present and discuss results. A final electronic survey was then conducted for final voting. Agreement ≥70% was considered consensus. Items near consensus were revised if feasible to achieve consensus in subsequent surveys.
Results:
Consensus was reached for 17 items for defining high-SSI risk, 17 items for preventing, 6 for diagnosing, and 9 for treating SSI in this high-risk population. After final voting, all 21 experts agreed to the publication and implementation of these items in their practice.
Conclusions:
We present a set of updated consensus-based BPGs for defining high-risk and preventing, diagnosing, and treating SSI in high-risk pediatric spine surgery. We believe that this BPG can limit variability in practice and decrease the incidence of SSI in pediatric spine surgery.
Level Of Evidence:
Not applicable.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

