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Updated: Aug 30, 2025

Determination of Glucan Chain Length Distribution of Glycogen Using the Fluorophore-Assisted Carbohydrate Electrophoresis FACE Method
Published on: March 31, 2022
Studies of carbohydrate-carbohydrate-interactions by atomic force microscopy employing functionalized
Julian C Thimm1, Eugen Beketow1, Joachim Thiem1
1Department of Chemistry, Faculty of Science, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany.
Abstract:
By Fischer glycosylation both anomers of 4-chlorobutyl gluco-as well as galactopyranosides were obtained and transformed into the corresponding 4-acetylthio-butyl glycopyranosides. Dependent on the precursors two straightforward routes were followed to obtain the appropriate 3-O-sulfated derivatives. Unsubstituted and sulfated glucopyranosides were attached to gold surfaces a gold tips. Their interactions were studied using atomic force microscopy for simulations of intercellular glycoside-based interactions and discussed in-depth.
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