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Microgeodic disease in an infant.

Katrina Frances Stranks1, Georgina Tiller2,3, Neelika Liyanage4

  • 1General Paediatrics, The Royal Children's Hospital, Parkville, Victoria, Australia katrinastranks@gmail.com.

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|August 29, 2022
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Summary
This summary is machine-generated.

This case report details an infant with temperature-sensitive finger and toe discoloration. Microgeodic disease, caused by cold-induced vasospasm, was diagnosed after extensive investigations excluded other causes.

Keywords:
DermatologyPaediatricsPrimary CareRheumatology

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Area of Science:

  • Pediatrics
  • Radiology
  • Rheumatology

Background:

  • Microgeodic disease is an uncommon, self-limiting condition.
  • It is characterized by bone lesions and is thought to result from cold-induced vasospasm.

Observation:

  • An infant presented with intermittent discoloration and swelling of digits correlating with ambient temperature changes.
  • Investigations revealed elevated inflammatory markers, phalangeal sclerotic lesions, and diffuse bone marrow edema.

Findings:

  • Infectious and inflammatory etiologies were ruled out based on clinical presentation and initial investigations.
  • Magnetic Resonance Imaging (MRI) was crucial in diagnosing microgeodic disease by revealing characteristic bone lesions and marrow edema.

Implications:

  • This case highlights the importance of considering microgeodic disease in infants with temperature-related digital symptoms.
  • Early diagnosis through advanced imaging like MRI can prevent unnecessary investigations for other conditions.
  • Understanding the pathophysiology, potentially linked to cold-induced vasospasm and avascular necrosis, aids in managing this rare condition.