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Updated: Aug 30, 2025
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Long-term Lung Abnormalities Associated with COVID-19 Pneumonia
Jeffrey P Kanne1, Brent P Little1, Jefree J Schulte1
1From the Department of Radiology (J.P.K.) and Department of Pathology and Laboratory Medicine (J.J.S.), University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, MC 3252, Madison, WI 53792-3252; Department of Radiology, Mayo Clinic, Jacksonville, Fla (B.P.L.); Department of Radiology, Massachusetts General Hospital, Boston, Mass (A.H.); and Departments of Radiology and Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (L.B.H.).
Abstract:
In the 3rd year of the SARS-CoV-2 pandemic, much has been learned about the long-term effects of COVID-19 pneumonia on the lungs. Approximately one-third of patients with moderate-to-severe pneumonia, especially those requiring intensive care therapy or mechanical ventilation, have residual abnormalities at chest CT 1 year after presentation. Abnormalities range from parenchymal bands to bronchial dilation to frank fibrosis. Less is known about the long-term pulmonary vascular sequelae, but there appears to be a persistent, increased risk of venothromboembolic events in a small cohort of patients. Finally, the associated histologic abnormalities resulting from SARS-CoV-2 infection are similar to those seen in patients with other causes of acute lung injury.
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