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Physiological Needs: Sensations and Predictions in the Insular Cortex
1Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.
Abstract:
Physiological needs create powerful motivations (e.g., thirst and hunger). Studies in humans and animal models have implicated the insular cortex in the neural regulation of physiological needs and need-driven behavior. We review prominent mechanistic models of how the insular cortex might achieve this regulation and present a conceptual and analytical framework for testing these models in healthy and pathological conditions.
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