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Updated: Aug 30, 2025

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
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Fluoride Transport and Inhibition Across CLC Transporters

Somayeh Asgharpour1,2, L América Chi3, Marc Spehr2,4

  • 1Institute for Advanced Simulations IAS-5 and Institute of Neuroscience and Medicine INM-9, Computational Biomedicine, Forschungszentrum Jülich, Jülich, Germany.

Handbook of Experimental Pharmacology
|August 30, 2022
PubMed

Keywords:
CLCCLCFChloride transportersElectrophysiologyFluoride transportersMetadynamicsMolecular dynamicsMultiscale simulationsMutagenesisQuantum mechanics/molecular mechanicsX-ray crystallography

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