Mapping research evidence on perinatal asphyxia within the sustainable development era in sub-Saharan Africa: a
Michael K Mensah1, Franky K Tano Kofi1, Monica Ansu-Mensah2
1Department of Public Health, Faculty of Health and Allied Sciences, Catholic University, College of Ghana, Fiapre, Sunyani, Ghana.
Insights
Perinatal asphyxia significantly contributes to newborn deaths in the WHO Africa Region. This review maps research on its burden, causes, and interventions to support Sustainable Development Goal 3.2.
Area of Science:
- Public Health
- Neonatal Medicine
- Global Health
Background:
- Neonatal mortality remains a critical challenge, with approximately 45% of under-five deaths occurring in the neonatal period within the World Health Organization (WHO) Africa Region.
- Addressing neonatal mortality is crucial for achieving Sustainable Development Goal (SDG) 3.2, necessitating innovative interventions.
- Perinatal asphyxia is a major contributor to neonatal mortality in the region, highlighting the need for focused research.
Purpose of the Study:
- To conduct a scoping review mapping existing research evidence on perinatal asphyxia among neonates in the WHO Africa Region.
- To identify research gaps and inform future studies and strategies aimed at reducing neonatal mortality due to perinatal asphyxia.
Main Methods:
- The review followed the Arksey and O'Malley framework, Levac et al. recommendations, and Joanna Briggs Institute checklist.
- Searched multiple databases (PubMed, SCOPUS, CINAHL, Web of Science) from January 2016 onwards, supplemented by grey literature searches.
- Included studies focused on the burden, contributing factors, clinical interventions, and prevention strategies for perinatal asphyxia in the WHO Africa Region, analyzed thematically.
Main Results:
- The review will systematically map the research landscape on perinatal asphyxia in the WHO Africa Region.
- Findings will elucidate the extent of research on the burden, causes, interventions, and prevention of perinatal asphyxia.
- Identified research gaps will be highlighted to guide future evidence generation.
Conclusions:
- This scoping review will provide a comprehensive overview of the research on perinatal asphyxia in the WHO Africa Region.
- The findings are expected to inform primary studies, systematic reviews, and meta-analyses, contributing to SDG 3.2.
- Dissemination through workshops, publications, conferences, and social media will ensure broad impact.
Background:
Approximately 45% of all under-five child deaths are among newborn infants, babies in their first 28 days of life, or the neonatal period every year in the World Health Organization (WHO) Africa Region. To facilitate the achievement of Sustainable Development Goal (SDG) 3.2, innovative interventions are needed to address this challenge. Thus, this scoping review aims to map research evidence on perinatal asphyxia among neonates in the WHO Africa Region.
Methods:
This scoping review will be guided by the Arksey and O'Malley framework, Levac et al. recommendations, and the Joanna Briggs Institute checklist for scoping reviews. Relevant published literature will be searched using a combination of keywords, Boolean terms, and Medical Subject Headings in the following databases: PubMed, SCOPUS, CINAHL, and Web of Science from January 2016 onwards. We will further search the World Health Organization and government websites, as well as the reference list of included studies for potentially eligible studies. This scoping review will include research evidence involving countries in the WHO Africa Region, with a focus on the burden of perinatal asphyxia, contributory/associated factors of perinatal asphyxia, clinical interventions for perinatal asphyxia, and interventions/strategies for the prevention of perinatal asphyxia in the SDGs era. Two reviewers will independently sort the studies to include and exclude, guided by the eligibility criteria. Also, the data from the included studies will be extracted and any discrepancies resolved using a third reviewer. Thematic analysis will be conducted, and the findings reported using both qualitative tables and figures. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Review (PRISMA-ScR) will be followed to report this study's results. Quality appraisal of the included studies will be done utilising the mixed methods appraisal tool version 2018.
Conclusion:
This scoping review results may reveal research evidence gaps to inform future primary studies, systematic reviews and meta-analyses; and possibly contribute towards the realisation of the SDG 3.2 by countries in the WHO Africa Region. The finding of this review will be disseminated using multiple channels such as workshops, peer review publications, conferences, and social media.
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