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Related Concept Videos

Photoluminescence: Applications01:14

Photoluminescence: Applications

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Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
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Photoluminescence: Fluorescence and Phosphorescence01:23

Photoluminescence: Fluorescence and Phosphorescence

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Photoluminescence is a process where a molecule absorbs light energy and re-emits it in the form of light. This phenomenon occurs when a substance absorbs photons, promoting its electrons to higher energy level excited states, followed by a relaxation process in which the electrons return to their original ground state energy levels and emit light. Photoluminescence is widely observed in various materials, including semiconductors, and organic and inorganic compounds.
A pair of electrons in a...
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Author Spotlight: Advancing Bioimaging and Therapy with Functional Nanomaterials
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Luminescence nanomaterials for biosensing applications.

Vaneet Kumar1, Diksha Bhatt1, Saruchi2

  • 1School of Natural Science, CT University, Ludhiana, Punjab, India.

Luminescence : the Journal of Biological and Chemical Luminescence
|August 31, 2022
PubMed
Summary

Persistent luminescence nanoparticles (PLNPs) offer enhanced sensitivity for molecule detection in biosensors. Their unique optical properties enable advanced applications in bioimaging and cancer therapy, with ongoing research focusing on novel developments.

Keywords:
SARS-CoV-2carbon nanotubegold nanoparticlesgrapheneimmunosensorsluminescence nanoparticlesnanodiamondsnanomaterialspolymer nanoparticlessemiconductor quantum dots

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Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Materials Science

Background:

  • Nanomaterials enhance biosensor sensitivity by immobilizing more bioreceptor parts at reduced volumes.
  • Various nanomaterials including carbon nanotubes, gold nanoparticles, and graphene are under investigation.
  • Persistent Luminescence Nanoparticles (PLNPs) are gaining attention for their unique optical properties and applications.

Purpose of the Study:

  • To review the classification and design of biosensors utilizing various nanomaterials.
  • To summarize recent advancements in Persistent Luminescence Nanoparticles (PLNPs) for biosensing, bioimaging, and cancer therapy.
  • To discuss synthesis methods, bioapplications, biomembrane modification, biosafety, and future prospects of PLNPs.

Main Methods:

  • Literature review and synthesis of existing research on nanomaterial-based biosensors.
  • Focus on Persistent Luminescence Nanoparticles (PLNPs) and their properties.
  • Analysis of applications in biosensing, cell tracking, bioimaging, and cancer therapy.

Main Results:

  • Nanomaterials significantly increase biosensor sensitivity.
  • PLNPs offer advantages like autofluorescence removal and ultra-long near-infrared afterglow emission.
  • PLNPs show promise in advanced biomedical applications including imaging and therapy.

Conclusions:

  • PLNPs are highly promising for sensitive biosensing and advanced biomedical applications.
  • Further research into novel PLNP types and their safety is crucial for broader clinical use.
  • Continued development is expected to overcome current challenges and expand therapeutic and diagnostic capabilities.